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Professor Emeritus Hans Laufer University of Connecticut Molecular and Cell Biology Torrey Life Science 91 North Eagleville Road, Unit 3125 Storrs, CT 06269-3125 Telephone: (860) 486-4117 Fax: (860) 486-4331 E-Mail: Laufer@uconn.edu

Education: Ph.D. Cornell University. Postdoctoral study: National Research Council Fellow, Carnegie Institution of Washington, Dept. of Embryology, Johns Hopkins University, Baltimore.

Research Interests: Gene regulation during development and reproduction; hormonal and molecular interactions; comparative endocrinology of invertebrates.
(1) studying hormones affecting reproduction, morphogenesis and metamorphosis of invertebrates and
(2) developing crustacean aquaculture techniques.
We are particularly interested in elucidating the signal transduction pathways involved in the regulation of reproductive development in invertebrates, especially Crustacea and Annelids.

Selected Publications:
Laufer, H., D. Borst, F.C. Baker, C. Carrasco,   M. Sinkus,   C.C. Reuter, L.W. Tsai, and D.S. Schooley. 1987 Identification of a juvenile hormone-like compound in a crustacean. Science 235:202-205

Laufer, H. and R. Downer (eds.). 1988. Invertebrate Endocrinology, Endocrinology of Selected Invertebrate Types, Vol.II.   A.R. Liss, Inc. New York, pp. 1-522.

Laufer, H.   Method for Increasing Crustacean Laval Production United States Patent & Trademark Office,Patent Number 5,161,481 (Nov 10, 1992)

Liu, L., H. Laufer, Y. Wang, and T. Hayes.   1997.   A Neurohormone regulating both methyl farnesoate synthesis and glucose metabolism in a crustacean.   Biochem. Biophys.   Research Communications.   237:694-701.

Liu, L.,H. Laufer, P.J. Gogarten, and M. Wang.   1997.   cDNA cloning of a mandibular organ inhibiting hormone from the spider crab Libinia emarginata. Invert.   Neuroscience. 3: 199-204

Biggers W.J., Laufer, H.,   1999.   Settlement and Metamorphosis of Capitella larvae induced by juvenile hormone-active compounds is mediated by protein kinase C and ion channels.   Biol. Bull. 196:187-190.

Laufer, H. and W.J. Biggers. 2001.   Unifying concepts learned from methyl farnesoate for invertebrate reproduction and post-embryonic development.   Amer. Zool. 41: 442-457.

Laufer, H. , Ahl,J.,Rotlant, G.,Baclaski, B., 2002. Ecdysteroids and methyl farnesoate control allometric growth and differentiation in a crustacean. Insect Biochem. Mol. Biol. 32: 205-210.

Laufer,H. , Johnson, M., Homola, E. .and Biggers, W. 2002. An assay for multiple MO activity. Proc. Euro. Comp. Endocrinol. 21: 399-404

Biggers W.J., and H. Laufer, 2004. Identification of juvenile hormone-active alkylphenols in the lobster Homarus americanus and in marine sediments. Biol. Bull. 206: 13-24

Laufer, H. and E. H. Baehrecke, 2004. "Regulation of Cell Growth, Differentiation, and Death during Metamorphosis. In: Cell Cycle and Growth Control: Biomolecular Regulation and Cancer". Gary S. Stein and Arthur Pardee, editors, Wiley- Liss publishers, NY. Pgs 369-395.

Laufer H., N. Demir, X. Pan, J.D. Stuart, and J.S.B. Ahl.   Methyl farnesoate controls adult male morphogenesis in the crayfish Procambarus clarki. 2005. J. Insect Physiol. 54: 379-384

Laufer, H., Demir, N., and Biggers, W. 2005. Response of the American lobster to the stress of shell disease. J. Shellfish Res. 24: 757-760.

Laufer, H. Demir, N., and Pan, X. 2005. Shell disease in the American lobster and its possible relations to alkyphenols. New England Aquarium Journal 05: 73-75.

Laufer, H. Demir, N. Capulong, C. Pan, X. Biggers, W. 2005. Hormonal responses of lobsters to stresses of Long Island Sound. Long Island Sound Research Conference Proceedings . 7: 41-43.